ConfigurationManager不保存设置

我认为您应该调用Save方法

ConfigurationManager.Save(ConfigurationSaveMode.Modified);ConfigurationManager.RefreshSection("appSettings");

编辑

为了能够保存，您必须使用OpenExeConfiguration方法返回的配置对象

//Create the objectConfiguration config = ConfigurationManager.OpenExeConfiguration(ConfigurationUserLevel.None);//make changesconfig.AppSettings.Settings["Username"].Value = txtUsername.Text;config.AppSettings.Settings["Password"].Value = txtPassword.Text;//save to apply changesconfig.Save(ConfigurationSaveMode.Modified);ConfigurationManager.RefreshSection("appSettings");

此处更多参考ConfigurationManager类