您无法通过发送消息来做到这一点，而是使用SendInput Windows API。
调用方法ClickOnPoint，这是表单单击事件的一个示例，
this.handle表单句柄也是如此，请注意，这些是发送窗口巫婆句柄的客户端坐标，您可以轻松地更改它并发送屏幕坐标，在这种情况下，您不需要或下面的ClientToScreen调用。
ClickonPoint(this.Handle, new Point(375, 340));
更新：现在使用tnx Tom，使用SendInput。
顺便说一句 我只使用了此示例所需的声明，还有更多漂亮的库：Windows Input Simulator（C＃SendInput包装器-
模拟键盘和鼠标）
public class ClickonPointTool { [Dllimport("user32.dll")] static extern bool ClientToScreen(IntPtr hWnd, ref Point lpPoint); [Dllimport("user32.dll")] internal static extern uint SendInput(uint nInputs, [MarshalAs(UnmanagedType.LPArray), In] INPUT[] pInputs, int cbSize);#pragma warning disable 649 internal struct INPUT { public UInt32 Type; public MOUSEKEYBDHARDWAREINPUT Data; } [StructLayout(LayoutKind.Explicit)] internal struct MOUSEKEYBDHARDWAREINPUT { [FieldOffset(0)] public MOUSEINPUT Mouse; } internal struct MOUSEINPUT { public Int32 X; public Int32 Y; public UInt32 MouseData; public UInt32 Flags; public UInt32 Time; public IntPtr ExtraInfo; }#pragma warning restore 649 public static void ClickonPoint(IntPtr wndHandle , Point clientPoint) { var oldPos = Cursor.Position; /// get screen coordinates ClientToScreen(wndHandle, ref clientPoint); /// set cursor on coords, and press mouse Cursor.Position = new Point(clientPoint.X, clientPoint.Y); var inputMouseDown = new INPUT(); inputMouseDown.Type = 0; /// input type mouse inputMouseDown.Data.Mouse.Flags = 0x0002; /// left button down var inputMouseUp = new INPUT(); inputMouseUp.Type = 0; /// input type mouse inputMouseUp.Data.Mouse.Flags = 0x0004; /// left button up var inputs = new INPUT[] { inputMouseDown, inputMouseUp }; SendInput((uint)inputs.Length, inputs, Marshal.SizeOf(typeof(INPUT))); /// return mouse Cursor.Position = oldPos; } }
