The skyscraper is made ---- new materials.

of 基本看得出是砖块还是其他建筑材料be made of 是可以看出原材料的,例:The sweater was made of woollen。毛衣是羊毛作的(可以看出的) be made from是不可以看出原材料的,例/:The paper is made from wood 纸是树木作的(看不出来的)