401.Progress so far has been very good,____,we are sure that the project will be completed on time.
A.However
B.Otherwise
C.Therefore
D.Besides
402. I'm certain David's told you his business trouble._____,it's no secret that he owes a lot of money to the bank.
A.However
B.Anyway
C.Therefore
D.Though
401.答案是C;however 不管怎样；otherwise 否则；therefore 所以；besides 除此以外、根据句意判断，前后句为因果关系，故选C。
402.答案是B;however表转折；anyway=anyhow反正，不管怎么说；therefore 因此；though虽然。句意为:…不管怎么说他欠银行很多钱不是秘密。
