what's the matter with her。这里的代词应为宾格，her在这里就是宾格的形式。简单的说就是这种句型是问某人有什么问题，直译就是什么事发生在某人身上了，就应该用宾格。
what's the matter with her用法三个知识点：
1. with 后要用宾格
2. you的主格和宾格相同
2. she的宾格是her
what's the matter with her同义句
What's wrong with her?
What's the problem with her?
What's business with her?
意思都是：她怎么了?或者,她发生什么事儿了?
